Simone Kleinendorst studied Molecular Mechanisms of Disease at the Radboud University. The subject of het master thesis was ‘Vps34 inhibition triggers a pro-inflammatory tumor immune response via the cGAS-STING pathway’, performed at Sprint Bioscience in Huddinge, Sweden. After graduating cum laude in August 2020, she started her PhD in September 2020 at the Department of Medical Imaging, Nuclear Medicine under supervision of Sandra Heskamp. The project is funded by the KWF and aims to understand radiobiological and immunological effects of CAIX-targeted radionuclide therapy.